We apply genetics, molecular and cellular biology, as well as bioinformatics and information technologies to solve applied problems in medicine and agriculture
Areas of expertise
We apply genome editing to real-life projects
We create genetic and cellular therapies for inherited diseases
We introduce advanced bioinformatics in medicine & agriculture
We develop vaccines and run epidemiology projects
We provide consulting services and scientific and technological advice to enterprises and investment firms
We run master classes on genetics and bioinformatics bespoked for employees (corporate), students and pupils.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Our Team
- Olga MityaevaPhD, MIPT alumni
#AAV #stem cells#vaccines - Eugene AlbertPhD, MSU & TU Dresden alumni
#bioinformatics #stem cells #endocrinology - Olga GlazovaMIPT & Mount Sinai
#CRISPR #viruses #sequencing #bioinformatics - Sofia Feoktistova
- Almaqdad Alsallum
- Nawar Sakr
- Denis Maksimov
- Andrey Devyatkin
and
47
employees
employees
biologists, virologists, chemists, technologists, bioinformatics, and data scientist
6
postdocs
postdocs
with work experience in the USA, Germany, and Israel
5
PhD students
PhD students
from all over the world engaged in laboratory projects
15
teachers
teachers
of courses for pupils, students, and employees of biotech companies and research labs
Projects
- Delivery system developmentCreation of new recombinant adeno-associated viruses with altered tropism with subsequent characterization in vitro and in vivo.
- Creation of therapies for genetic diseasesDevelopment of a progressive gene therapy for genetic diseases based on AAV and gene therapy models.
- Avian Influenza
ResearchResearch into the epidemiology and evolution of avian influenza, as well as the creation of transgenic breeds of poultry resistant to the virus. - Screening
researchPopulation studies, including the study of the cellular immune response to SARS-COV-2 in the Moscow population.
Partners
Публикации
- The Journal of Immunology, 2022Komissarov AA, Dolzhikova IV, Efimov GA, Logunov DY, Mityaeva O, Molodtsov IA, Naigovzina NB, Peshkova IO, Shcheblyakov DV, Volchkov P, Gintsburg AL, Vasilieva E.
Boosting of the SARS-CoV-2-Specific Immune Response after Vaccination with Single-Dose Sputnik Light Vaccine. J Immunol. 2022 Mar 1;208(5):1139-1145. doi: 10.4049/jimmunol.2101052. Epub 2022 Jan 31. PMID: 35101893. - Vaccines, 2022Deviatkin, A.A.; Simonov, R.A.; Trutneva, K.A.; Maznina, A.A.; Khavina, E.M.; Volchkov, P.Y. Universal Flu mRNA Vaccine: Promises, Prospects, and Problems. Vaccines 2022, 10, 709. https://doi.org/10.3390/vaccines10050709
- The Journal of Immunology, 2022Ivan A Molodtsov, Evgenii Kegeles, Alexander N Mitin, Olga Mityaeva, Oksana E Musatova, Anna E Panova, Mikhail V Pashenkov, Iuliia O Peshkova, Almaqdad Alsalloum, Walaa Asaad
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)–Specific T Cells and Antibodies in Coronavirus Disease 2019 (COVID-19) Protection: A Prospective Study
Clinical Infectious Diseases, Volume 75, Issue 1, 1 July 2022, Pages e1–e9, https://doi.org/10.1093/cid/ciac278 - Viruses, 2022Beloukhova, M.I.; Lukashev, A.N.; Volchkov, P.Y.; Zamyatnin, A.A., Jr.; Deviatkin, A.A.
Robust AAV Genotyping Based on Genetic Distances in Rep Gene That Are Maintained by Ubiquitous Recombination. Viruses 2022, 14, 1038. https://doi.org/10.3390/v14051038 - Pathogens, 2021Blagodatski, A.; Trutneva, K.; Glazova, O.; Mityaeva, O.; Shevkova, L.; Kegeles, E.; Onyanov, N.; Fede, K.; Maznina, A.; Khavina, E.; Yeo, S.-J.; Park, H.; Volchkov, P.
Avian Influenza in Wild Birds and Poultry: Dissemination Pathways, Monitoring Methods, and Virus Ecology. Pathogens 2021, 10, 630. https://doi.org/10.3390/pathogens10050630 - Molecular Therapy - Methods &Clinical Development, 2021Oswald, J; Kegeles, E.; Minelli, T.; Volchkov, P. and Baranov, P. Transplantation of miPSC/mES-derived Retinal Ganglion Cells into healthy and glaucomatous retinas, Molecular Therapy - Methods &Clinical Development, 2021, doi: 10.1016/j.omtm.2021.03.004
Laboratory Vacancies
- BioinformaticianWe are searching for a bioinformatician for a medical genomics project
- Lab AssistantWe are searching for a lab assistant for cellular, embryological and molecular biological work
- Research Fellow: Gene TherapyWe are searching for an experienced researcher to manage the development of gene therapy approaches of a number of projects
- Senior Bioinformatician
/PostdocWe are searching for an experienced bioinformatician to analyze big genomic data, participate in analytical reports, and write scientific articles - Research Fellow: VirologyWe are looking for an experienced researcher who will lead a number of projects in the fields of virology and synthetic biology
- BiotechnologistWe are looking for a biotechnologist who, under the guidance of an experienced specialist, will develop vectors according to ready-made protocols
- AAV Facility HeadWe are searching for an experienced biotechnologist to lead the AAV production. They are to take over process establishment and management of production during scaling and further work
- Research Associate for a Recombinant AAV Development ProjectWe are searching for an experienced researcher to lead a number of projects in the fields of virology and synthetic biology
No suitable vacancy, but you want to work with us? Email us with your CV and something about yourself, and we'll try to work something out
Journal Club
31 of March
17:00
Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine
Ekaterina Kuznetsova
18:00
Viable offspring derived from single unfertilized mammalian oocytes
Anastasia Reshetnikova
7 of April
18:00
Article
Name
18:00
Article
Name
14 of April
Join our Journal Club
Anybody can come to one of our Journal Clubs as a spectator. If you would like to present a paper, please contact us!
Moscow region, Dolgoprudny
Institutsky lane 9, building 7
Moscow Institute of Physics and Technology
Phystech.Bio building
Institutsky lane 9, building 7
Moscow Institute of Physics and Technology
Phystech.Bio building
Our lab
- Team
- Projects
- Partners
Education
- Journal Club
Contact us
- genlabllc@gmail.com
(с)
Genome Engineering Lab of MIPT,
2015 - 2022
2015 - 2022