We apply genetics, molecular and cellular biology, as well as bioinformatics and information technologies to solve applied problems in medicine and agriculture
Areas of expertise
We apply genome editing to real-life projects
We create genetic and cellular therapies for inherited diseases
We introduce advanced bioinformatics in medicine & agriculture
We develop vaccines and run epidemiology projects
We provide consulting services and scientific and technological advice to enterprises and investment firms
We run master classes on genetics and bioinformatics bespoked for employees (corporate), students and pupils.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Our Team
Olga Mityaeva
PhD, MIPT alumni
#AAV #stem cells#vaccines
Eugene Albert
PhD, MSU & TU Dresden alumni
#bioinformatics #stem cells #endocrinology
Olga Glazova
MIPT & Mount Sinai
#CRISPR #viruses #sequencing #bioinformatics
and
30
employees
biologists, virologists, chemists, technologists, bioinformatics, and data scientist
6
postdocs
with work experience in the USA, Germany, and Israel
6
PhD students
from all over the world engaged in laboratory projects
10
teachers
of courses for pupils, students, and employees of biotech companies and research labs
Projects
Delivery system development
Creation of new recombinant adeno-associated viruses with altered tropism with subsequent characterization in vitro and in vivo.
Creation of therapies for retina diseases
Development of a progressive gene therapy for congenital retinal diseases based on AAV and gene therapy models for retinal diseases.
Avian Influenza
Research
Research into the epidemiology and evolution of avian influenza, as well as the creation of transgenic breeds of poultry resistant to the virus.
Screening
research
Population studies, including the study of the cellular immune response to SARS-COV-2 in the Moscow population.
Partners
Publications
The Journal of Immunology, 2022
Komissarov AA, Dolzhikova IV, Efimov GA, Logunov DY, Mityaeva O, Molodtsov IA, Naigovzina NB, Peshkova IO, Shcheblyakov DV, Volchkov P, Gintsburg AL, Vasilieva E. Boosting of the SARS-CoV-2-Specific Immune Response after Vaccination with Single-Dose Sputnik Light Vaccine. J Immunol. 2022 Mar 1;208(5):1139-1145. doi: 10.4049/jimmunol.2101052. Epub 2022 Jan 31. PMID: 35101893.
PLoS Genetics, 2021
Neverov, A.D., Popova, A.V., Fedonin, G.G., ...Klink, G.V., Bazykin, G.A. Episodic evolution of coadapted sets of amino acid sites in mitochondrial proteins. PLoS Genetics, 2021, 17(1), e1008711 https://doi.org/10.1371/journal.pgen.1008711
Molecular Therapy - Methods &Clinical Development, 2021
Oswald, J; Kegeles, E.; Minelli, T.; Volchkov, P. and Baranov, P. Transplantation of miPSC/mES-derived Retinal Ganglion Cells into healthy and glaucomatous retinas, Molecular Therapy - Methods &Clinical Development, 2021, doi: 10.1016/j.omtm.2021.03.004
Frontiers in Cellular Neuroscience, 2020
Evgenii Kegeles, Anton Naumov, Evgeny A. Karpulevich, Pavel Volchkov, Petr Baranov; Convolutional neural networks can predict retinal differentiation in retinal organoids; Frontiers in Cellular Neuroscience; doi: 10.3389/fncel.2020.00171
Transl. Vis. Sci. Technol., 2020.
Kegeles, E.; Perepelkina, T.; Baranov, P. Semi-automated approach for retinal tissue differentiation. Transl. Vis. Sci. Technol. 2020., Q1 (Ophthalmology, Biomedical engineering), IF=2.57 https://doi.org/10.1167/tvst.9.10.24
Ticks and Tick-borne Diseases, 2020
Safonova, M.V., Gmyl, A.P., Lukashev, A.N.,Fedonin, G.G Bulanenko, V.P., Dedkov, V.G.Genetic diversity of Kemerovo virus and phylogenetic relationships within the Great Island virus genetic group. Ticks and Tick-borne Diseases, 2020, 11(2), 101333
Laboratory Vacancies

No suitable vacancy, but you want to work with us? Email us with your CV and something about yourself, and we'll try to work something out
Journal Club
23 september
16 september
Anastasia Soroka
Ksenia Trutneva
7 october
Evgeniy Albert
Anna Navoykova
Join our Journal Club
Anybody can come to one of our Journal Clubs as a spectator. If you would like to present a paper, please contact us!
+7 (915) 377-11-07
genlabllc@gmail.com
Moscow region, Dolgoprudny
Institutsky lane 9, building 7
Moscow Institute of Physics and Technology
Phystech.Bio building
Our lab
  • Team
  • Projects
  • Partners
Education
  • Journal Club
Contact us
  • +7 (915) 377-11-07
  • genlabllc@gmail.com
(с)
Genome Engineering Lab of MIPT,
2015 - 2022