We apply genetics, molecular and cellular biology, as well as bioinformatics and information technologies to solve applied problems in medicine and agriculture
Areas of expertise
  • We apply genome editing to real-life projects
  • We create genetic and cellular therapies for inherited diseases
  • We introduce advanced bioinformatics in medicine & agriculture
  • We develop vaccines and run epidemiology projects
  • We provide consulting services and scientific and technological advice to enterprises and investment firms
  • We run master classes on genetics and bioinformatics bespoked for employees (corporate), students and pupils.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Pavel Volchkov
PhD, Director of the Life Sciences Research Center of MIPT, Head of the Genome Engineering Lab, Head of Institute of the Personalized Medicine of The National Endocrinology Center.
A recognized expert in molecular biology, genome engineering, stem cells, and viruses. MSU alumni, postdoctoral fellow of University of Chicago and Harvard Medical School.
Our Team
  • Olga Mityaeva
    PhD, MIPT alumni
    #AAV #stem cells#vaccines
  • Eugene Albert
    PhD, MSU & TU Dresden alumni
    #bioinformatics #stem cells #endocrinology
  • Olga Glazova
    MIPT & Mount Sinai
    #CRISPR #viruses #sequencing #bioinformatics
  • Sofia Feoktistova
  • Almaqdad Alsallum
  • Nawar Sakr
  • Denis Maksimov
  • Andrey Devyatkin
and
80
employees
biologists, virologists, chemists, technologists, bioinformatics, and data scientist
10
postdocs
with work experience in the USA, Germany, and Israel
5
PhD students
from all over the world engaged in laboratory projects
15
teachers
of courses for pupils, students, and employees of biotech companies and research labs
Projects
  • Delivery system development
    Creation of new recombinant adeno-associated viruses with altered tropism with subsequent characterization in vitro and in vivo.
  • Creation of therapies for genetic diseases
    Development of a progressive gene therapy for genetic diseases based on AAV and gene therapy models.
  • Avian Influenza
    Research
    Research into the epidemiology and evolution of avian influenza, as well as the creation of transgenic breeds of poultry resistant to the virus.
  • Screening
    research
    Population studies, including the study of the cellular immune response to SARS-COV-2 in the Moscow population.
Partners
PUBLICATIONS
  • Frontiers in Genetics, 2023
    Albert E. A., Kondratieva O. A., Baranova E. E., Sagaydak O. V., Belenikin M. S., Zobkova G. Y., Kuznetsova E. S., Deviatkin A. A., Zhurov A. A., Karpulevich E. A., Volchkov P. Y., Vorontsova M. V.,

    Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations, Frontiers in Genetics, VOLUME 14, 2023,10.3389/fgene.2023.1086709
  • Heliyon, 2023
    Walaa Asaad, Polina Volos, Denis Maksimov, Elena Khavina, Andrei Deviatkin, Olga Mityaeva, Pavel Volchkov

    AAV genome modification for efficient AAV production, Heliyon, Volume 9, Issue 4, 2023, e15071, https://doi.org/10.1016/j.heliyon.2023.e15071.
  • The Journal of Immunology, 2022
    Komissarov AA, Dolzhikova IV, Efimov GA, Logunov DY, Mityaeva O, Molodtsov IA, Naigovzina NB, Peshkova IO, Shcheblyakov DV, Volchkov P, Gintsburg AL, Vasilieva E.

    Boosting of the SARS-CoV-2-Specific Immune Response after Vaccination with Single-Dose Sputnik Light Vaccine. J Immunol. 2022 Mar 1;208(5):1139-1145. doi: 10.4049/jimmunol.2101052. Epub 2022 Jan 31. PMID: 35101893.
  • Vaccines, 2022
    Deviatkin, A.A.; Simonov, R.A.; Trutneva, K.A.; Maznina, A.A.; Khavina, E.M.; Volchkov, P.Y. Universal Flu mRNA Vaccine: Promises, Prospects, and Problems. Vaccines 2022, 10, 709. https://doi.org/10.3390/vaccines10050709
  • The Journal of Immunology, 2022
    Ivan A Molodtsov, Evgenii Kegeles, Alexander N Mitin, Olga Mityaeva, Oksana E Musatova, Anna E Panova, Mikhail V Pashenkov, Iuliia O Peshkova, Almaqdad Alsalloum, Walaa Asaad

    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)–Specific T Cells and Antibodies in Coronavirus Disease 2019 (COVID-19) Protection: A Prospective Study
    Clinical Infectious Diseases, Volume 75, Issue 1, 1 July 2022, Pages e1–e9, https://doi.org/10.1093/cid/ciac278
  • Viruses, 2022
    Beloukhova, M.I.; Lukashev, A.N.; Volchkov, P.Y.; Zamyatnin, A.A., Jr.; Deviatkin, A.A.
    Robust AAV Genotyping Based on Genetic Distances in Rep Gene That Are Maintained by Ubiquitous Recombination. Viruses 2022, 14, 1038. https://doi.org/10.3390/v14051038
  • Pathogens, 2021
    Blagodatski, A.; Trutneva, K.; Glazova, O.; Mityaeva, O.; Shevkova, L.; Kegeles, E.; Onyanov, N.; Fede, K.; Maznina, A.; Khavina, E.; Yeo, S.-J.; Park, H.; Volchkov, P.

    Avian Influenza in Wild Birds and Poultry: Dissemination Pathways, Monitoring Methods, and Virus Ecology. Pathogens 2021, 10, 630. https://doi.org/10.3390/pathogens10050630
  • Molecular Therapy - Methods &Clinical Development, 2021
    Oswald, J; Kegeles, E.; Minelli, T.; Volchkov, P. and Baranov, P. Transplantation of miPSC/mES-derived Retinal Ganglion Cells into healthy and glaucomatous retinas, Molecular Therapy - Methods &Clinical Development, 2021, doi: 10.1016/j.omtm.2021.03.004
No suitable vacancy, but you want to work with us? Email us with your CV and something about yourself, and we'll try to work something out
Join our Journal Club
Anybody can come to one of our Journal Clubs as a spectator. If you would like to present a paper, please contact us!
Moscow region, Dolgoprudny
Institutsky lane 9, building 7
Moscow Institute of Physics and Technology
Phystech.Bio building
Our lab
  • Team
  • Projects
  • Partners
Education
  • Journal Club
Contact us
  • genlabllc@gmail.com
(с)
Genome Engineering Lab of MIPT,
2015 - 2022